https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:12355 Sat 24 Mar 2018 08:18:31 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:12449 40 mV shift of the K⁺ equilibrium potential and a rise in effective K⁺ concentration (>50 mM) in the intercellular space. Together these data suggest K⁺ accumulation in the intercellular space accounts for the different responses in isolated and embedded type I hair cells. To test this notion, we exposed the preparation to hyperosmotic solutions to enlarge the intercellular space. As predicted, the K⁺ accumulation effects were reduced; however, a fit of our data with a classic diffusion model suggested K⁺ permeability, rather than the intercellular space, had been altered by the hyperosmotic change. These results support the notion that under depolarizing conditions Substantial K⁺ accumulation occurs in the space between type I hair cells and calyx. The extent of K⁺ accumulation during normal synaptic transmission, however, remains to be determined.]]> Sat 24 Mar 2018 08:17:49 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:11513 Sat 24 Mar 2018 08:11:08 AEDT ]]>